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Post by jorgeandthekraken on Nov 5, 2021 8:17:09 GMT -5
This seems like a really big deal.
90% efficacy against hospitalization and death in adults already considered high-risk. Like with Merck's pill, the trial was halted early due to the great results...but unlike Merck's pill, this one is a protease inhibitor (in line with the oral anti-HIV meds in wide use), so the concerns about mutagenicity that are being batted around about Molnupiravir won't apply. I'm sure the nuts will still find something to fearmonger about, here, but for the rest of us, this could really move the needle. With this, plus Molnupiravir, plus vaccination, we have enough tools that people dying from this disease, at least in places where access to these drugs is possible, should be staggeringly less likely than it was a year and change ago.
Also, big ups to anyone who invested in Pfizer on a whim in 2019.
EDITED TO ADD: The only caveat is that best results were seen within 3 days of symptom onset, which is a tough go in a world in which getting PCR test results back can take 48 hours or more. Results if the regimen was started within 5 days still weren't bad (around 80%, if I remember what I read correctly), but still, a massive ramp-up in testing capacity should be a big priority moving forward if we really want to get out of a pandemic state.
Do you want to dance while also thinking about all the ways you've failed as a human?
UPCOMING SHOWS 6/8 and maybe 6/9 - Governors Ball 8/17 - King Gizzard & the Lizard Wizard @ Forest Hills 9/4 - Pearl Jam @ MSG 9/7 - Pearl Jam @ Wells Fargo Center 9/11 - St. Vincent @ Brooklyn Paramount 9/19 - Stars @ Music Hall of Williamsburg 9/20 - Khruangbin @ Forest Hills
Post by Teddy Flair on Nov 10, 2021 21:56:39 GMT -5
Hosting karaoke tonight, I wipe off the mics with sanitizer and a towel after every singer, some old dude just said "you don't have to do that, I've already had covid." 🧐
Hosting karaoke tonight, I wipe off the mics with sanitizer and a towel after every singer, some old dude just said "you don't have to do that, I've already had covid." 🧐
Do you want to dance while also thinking about all the ways you've failed as a human?
UPCOMING SHOWS 6/8 and maybe 6/9 - Governors Ball 8/17 - King Gizzard & the Lizard Wizard @ Forest Hills 9/4 - Pearl Jam @ MSG 9/7 - Pearl Jam @ Wells Fargo Center 9/11 - St. Vincent @ Brooklyn Paramount 9/19 - Stars @ Music Hall of Williamsburg 9/20 - Khruangbin @ Forest Hills
Hosting karaoke tonight, I wipe off the mics with sanitizer and a towel after every singer, some old dude just said "you don't have to do that, I've already had covid." 🧐
People are doing karaoke? Like...inside?
in this area they never stopped. I only picked up the gig a couple months ago
Hosting karaoke tonight, I wipe off the mics with sanitizer and a towel after every singer, some old dude just said "you don't have to do that, I've already had covid." 🧐
People are doing karaoke? Like...inside?
I've built or recorded multiple events (indoor) that use the same microphones, and as a recordist the mics I use are re-used on different people. Wiping a handheld mic makes sense but I'll tell you that because the pressures of speed in the industry, they often don't get wiped or anything on that level because clients would need to change their expectations.
Last Edit: Nov 11, 2021 12:34:38 GMT -5 by Deleted - Back to Top
Got my Moderna booster yesterday. Pretty much the same reaction I had to the second shot -- knocked me down for about four hours on day two, now feeling fine.
how strict are pharmacies on checking ID's of 4 year olds who look like 5 year olds ?
VERY strict. We could lose our license. Sorry.
Oh wow. That’s crazy. My 5 year old got his yesterday at a county vax clinic and they just asked if he was 5 and did t require any proof at all. I’m sure they have his information somewhere but didn’t require anything.
1/17 Spafford 2/7 Greensky Bluegrass 3/17 Cool Cool Cool 3/28 Ekoostik Hookah 7/10 Jason Mraz 7/11 Chris Stapleton 7/12 Red Hot Chili Peppers 7/13 Buffalo Ska Fest
Hosting karaoke tonight, I wipe off the mics with sanitizer and a towel after every singer, some old dude just said "you don't have to do that, I've already had covid." 🧐
People are doing karaoke? Like...inside?
I'm enrolling my kid in preschool at the YMCA soon and I was shocked to see at least 75% of the people inside the gym not wearing masks.
Luckily the preschool has a separate entrance and they all wear masks.
I'm enrolling my kid in preschool at the YMCA soon and I was shocked to see at least 75% of the people inside the gym not wearing masks.
Luckily the preschool has a separate entrance and they all wear masks.
NY is still pretty mask heavy but, while public schools have been required to wear masks, childcare centers have not. Every day I drop my kids off with masks on and I'm assuming that they are gone as soon as they go through those doors. (Parents are not allowed into the building.)
Hosting karaoke tonight, I wipe off the mics with sanitizer and a towel after every singer, some old dude just said "you don't have to do that, I've already had covid." 🧐
Good morning. Is it time to start moving back to normalcy?
Cable car riders in San Francisco.Jim Wilson/The New York Times If not now … Among the Covid experts I regularly talk with, Dr. Robert Wachter is one of the more cautious. He worries about “long Covid,” and he believes that many people should receive booster shots. He says that he may wear a mask in supermarkets and on airplanes for the rest of his life.
Yet Wachter — the chair of the medicine department at the University of California, San Francisco — also worries about the downsides of organizing our lives around Covid. In recent weeks, he has begun to think about when most of life’s rhythms should start returning to normal. Increasingly, he believes the answer is: Now.
This belief stems from the fact that the virus is unlikely to go away, ever. Like most viruses, it will probably keep circulating, with cases rising sometimes and falling other times. But we have the tools — vaccines, along with an emerging group of treatments — to turn it into a manageable virus, similar to the seasonal flu.
Given this reality, Wachter, who’s 64, has decided to resume more of his old activities and accept the additional risk that comes with them, much as we accept the risk of crashes when riding in vehicles.
He has begun eating in indoor restaurants again and playing poker, unmasked, with vaccinated friends. He has taken airplanes to visit relatives. He hosted a medical conference in downtown San Francisco with a few hundred masked and vaccinated attendees.
“I’m still going to be thoughtful and careful,” Wachter told The San Francisco Chronicle. But “if I’m not going to do it now, I’m probably saying that I’m not going to do it for the next couple of years, and I might be saying I’m not doing it forever.”
The hospitalization statistics in highly vaccinated communities help explain Wachter’s attitude. In Seattle (which publishes detailed data), the daily Covid hospitalization rate for vaccinated people has been slightly above one in one million. By comparison, the flu hospitalization rate in a typical year in the U.S. is more than twice as high. For most vaccinated people in a place like Seattle or San Francisco, Covid already resembles just another virus.
The risks are also low for unvaccinated children because Covid tends to be mild for them. (Plus, any child 5 or older can now be vaccinated.) For young children, Covid looks like a normal flu, if not a mild one:
Source: Centers for Disease Control and Prevention As for long Covid, it is real but rare. It’s also not unique. The flu and other viruses also cause mysterious, lasting problems for a small share of people, studies show.
The bottom line is that Covid now presents the sort of risk to most vaccinated people that we unthinkingly accept in other parts of life. And there is not going to be a day when we wake up to headlines proclaiming that Covid is defeated. In many ways, the future of the virus has arrived.
All of which raises the question of which precautions should end — now or soon — and which should become permanent.
Should offices remain mostly empty? Should schools require children and teachers to wear masks? Should classrooms go remote again when they identify a new Covid case? (In Boston, a K-8 school closed for 10 days starting Wednesday because of an outbreak.) For how long should individuals organize their own lives around a fear of Covid?
Most of these questions are tricky, and a few factors can guide the decision-making, epidemiologists say.
1. Local spread The lower the rate of Covid spread in a community, the less risk to everyone. The C.D.C. defines a low rate of transmission as, among other things, fewer than 10 new daily cases per 100,000 people. Most of the country is well above that threshold, but parts of the San Francisco, Atlanta, Dallas, Houston, Los Angeles, Miami, New York and Washington areas are below it. (You can look up your county here.)
Nevada has taken an approach that experts like Julia Raifman of Boston University have praised: The state will remove mask mandates after cases have fallen below a certain level. Joseph Allen of Harvard, criticizing the different approach in many other places, has said, “We’re sleepwalking into policy because we’re not setting goals.”
One complication: Nationally, new cases have risen modestly in recent weeks, though they are still far below the levels of late summer. If new cases accelerate as the weather gets colder and more activity moves indoors, it may call for caution.
2. Illness, not cases Still, with vaccines widely available and treatments increasingly so, caseloads are not as important a metric as they once were. They “are becoming less and less useful,” as The Atlantic’s Sarah Zhang has written. More telling measures are hospitalizations and deaths.
The treatments for people who contract Covid are especially important here. Pfizer’s pill regimen, which seems especially effective, reduces the risk of hospitalization by more than 80 percent. These treatments are another step toward turning Covid into a normal virus rather than one that dominates life.
3. Vulnerability Different people face different levels of Covid risk. For most vaccinated people and children, the risks are extremely low. But for some immunocompromised people — like those who have received organ transplants — the risks are higher. The same is true among people in their 80s and 90s.
Greater precautions make sense for vulnerable people. They will also particularly benefit if rapid Covid testing ever becomes widely available in the U.S., allowing them to socialize more confidently.
There is a flip side to this point: The aggregate statistics on Covid deaths and hospitalizations exaggerate the risk to most Americans, because a disproportionate share of severe illness occurs among people with specific medical vulnerabilities.
4. Cost vs. benefit Wachter told me that he might always wear a mask while grocery shopping or flying on a plane because the costs of having a covered face and a muzzled voice in those settings are virtually zero. He isn’t usually trying to have a conversation with somebody. And a mask can help protect him from all sorts of respiratory viruses.
Unfortunately, the costs of most Covid interventions are higher. Masks inhibit communication, especially for young children and the hard of hearing. (Wachter also says he expects conferences eventually to be maskless.) Remote school has been a failure. Remote office work hampers collaboration. Social isolation causes mental-health problems.
When The Washington Post recently asked Jennifer Nuzzo, an epidemiologist at Johns Hopkins University, when the pandemic would end, she replied: “It doesn’t end. We just stop caring. Or we care a lot less.” She added, “I think for most people, it just fades into the background of their lives.”
I realize that answer may sound jarring, but the alternative — a society permanently dominated by Covid — is jarring, too. Eventually, the costs of organizing our lives around the virus will exceed the benefits. In some cases, we may have already reached that point.
5.5/four tet, daphni b2b floating points, avalon emerson 5.12/neil young 5.19/mannequin pussy 5.21/serpentwithfeet 5.25/hozier 6.12-16/bonnaroo 6.28/goose 6.29/goose 9.17/the national + the war on drugs 9.23/sigur ros 9.27-29/making time 10.17/air
Austria has instituted an unvaccinated quarantine.
The leader of the far-right opposition Freedom Party vowed to combat the new restrictions by “all parliamentary and legal means we have available.” Herbert Kickl said that “2 million people are being practically imprisoned without having done anything wrong.”
Wait for it
On Monday, Kickl announced on Facebook that he had tested positive for the virus and must self-isolate for 14 days, so he won’t be able to attend a protest in Vienna planned for Saturday.
Stepdad has it, hopefully my mom doesn’t get it too. The only two unvaccinated people in my sphere. I imagine they’ll be fine but also ughhh
Last Edit: Nov 19, 2021 16:44:06 GMT -5 by Jaz - Back to Top
5.5/four tet, daphni b2b floating points, avalon emerson 5.12/neil young 5.19/mannequin pussy 5.21/serpentwithfeet 5.25/hozier 6.12-16/bonnaroo 6.28/goose 6.29/goose 9.17/the national + the war on drugs 9.23/sigur ros 9.27-29/making time 10.17/air
Stepdad has it, hopefully my mom doesn’t get it too. The only two unvaccinated people in my sphere. I imagine they’ll be fine but also ughhh
Fuck, dude. I’ll start the sacrifices here in a bit. I’m so sorry.
Mrs and I got boosted today and the kiddos got first doses. If you live in Chesterfield County in Virginia, pretty sure you already knew this. I know everyone in the Publix did. Everyone is okay thus far. We blew $80 at Target after and nobody remembered why they got toys in the first place.
By a happy accident, I had Pokémon Brilliant Diamond + Shining Pearl 2 pack sitting on the porch when we got home, too. Still gotta budget in for 21 days now.
Hey all, caught a breakthrough cases at desert daze last last week and lost my sense of smell. Has anyone else that got it lost theirs and how long didv it take to come back, if at all? I honestly have very little appetite now because of it
Hey all, caught a breakthrough cases at desert daze last last week and lost my sense of smell. Has anyone else that got it lost theirs and how long didv it take to come back, if at all? I honestly have very little appetite now because of it
sorry man, i had one in august and that was my only symptom. took about 1-2 months for it to come back near fully but i came out of it disliking IPAs despite loving them before. so it may change your taste buds
Hey all, caught a breakthrough cases at desert daze last last week and lost my sense of smell. Has anyone else that got it lost theirs and how long didv it take to come back, if at all? I honestly have very little appetite now because of it
That sucks. I'm sorry.
I suppose if that happened to me I would focus on only eating healthy stuff since I won't know if it tastes good or not.
Hey all, caught a breakthrough cases at desert daze last last week and lost my sense of smell. Has anyone else that got it lost theirs and how long didv it take to come back, if at all? I honestly have very little appetite now because of it
sorry man, i had one in august and that was my only symptom. took about 1-2 months for it to come back near fully but i came out of it disliking IPAs despite loving them before. so it may change your taste buds
Yeah, I’m not certain I had covid because my pcr test came back negative, but I was sick in mid-September and fully lost my smell and taste. It started gradually coming back after a few days, but it still is not 100% normal. Like, I had an appetite and could enjoy food again within a week or so, but as of now, I don’t feel like things have as much flavor as they used to. My sister-in-law had it in December, and when I asked her in September, she said certain things still didn’t taste right to her then so I think it can have a pretty lasting effect, but it does get significantly better.
Hey all, caught a breakthrough cases at desert daze last last week and lost my sense of smell. Has anyone else that got it lost theirs and how long didv it take to come back, if at all? I honestly have very little appetite now because of it
That sucks. I'm sorry.
I suppose if that happened to me I would focus on only eating healthy stuff since I won't know if it tastes good or not.
That's funny... I was thinking the same thing, and also just drinking my coffee black for the caffeine