Whether it's your first Bonnaroo or you’re a music festival veteran, we welcome you to Inforoo.
Here you'll find info about artists, rumors, camping tips, and the infamous Roo Clues. Have a look around then create an account and join in the fun. See you at Bonnaroo!!
Only two of six vaccine candidates that have the backing of the federal government – from Moderna and Pfizer – are currently in active Phase III clinical trials, and both require individuals to take two doses, three to four weeks apart. Both also require complex cold shipment and storage conditions. A third vaccine from AstraZeneca, which must be maintained in minus-20 degrees storage conditions, entered Phase III trials in the United States on Monday, but has recruited only three dozen people so far, Corey said.
I don’t get the second Moderna shot until the end of September. Then they have to get my blood work for several months to see if it’s even working. I know Cheeto thinks he can push this so he can get re-elected, but the medical community can’t and I hope, won’t put this vaccine out there before it’s ready. That would be disastrous.
It sounds like late Q1 2021 could be a possibility though from your experience. That could potentially save the festival season for us here.
Post by piggy pablo on Sept 3, 2020 15:55:09 GMT -5
Myocarditis is an inflammation of the middle layer of the heart wall. It is treatable and typically goes away after a few months but can lead to fatal complications, including heart failure.
Myocarditis is an inflammation of the middle layer of the heart wall. It is treatable and typically goes away after a few months but can lead to fatal complications, including heart failure.
i don't know shit about fuck, but the mayo clinic page says "In mild cases, persons should avoid competitive sports for at least three to six months."
Question: say I get a first round vaccine that barely passes the sniff test of 50% effective. Given that I’m young and healthy, I’m willing to take that risk of me still catching the virus (would still wear my mask and distance when possible if it’s only 50% effective) but if I do, does that mean I’ll still have some sort of immunity and it won’t hit me as hard as it otherwise could?
Question: say I get a first round vaccine that barely passes the sniff test of 50% effective. Given that I’m young and healthy, I’m willing to take that risk of me still catching the virus (would still wear my mask and distance when possible if it’s only 50% effective) but if I do, does that mean I’ll still have some sort of immunity and it won’t hit me as hard as it otherwise could?
Related question: When people say a vaccine is 50% effective, does that mean it only protects against 50% of exposures or it's only provides protection for 50% of people?
Question: say I get a first round vaccine that barely passes the sniff test of 50% effective. Given that I’m young and healthy, I’m willing to take that risk of me still catching the virus (would still wear my mask and distance when possible if it’s only 50% effective) but if I do, does that mean I’ll still have some sort of immunity and it won’t hit me as hard as it otherwise could?
Question: say I get a first round vaccine that barely passes the sniff test of 50% effective. Given that I’m young and healthy, I’m willing to take that risk of me still catching the virus (would still wear my mask and distance when possible if it’s only 50% effective) but if I do, does that mean I’ll still have some sort of immunity and it won’t hit me as hard as it otherwise could?
Related question: When people say a vaccine is 50% effective, does that mean it only protects against 50% of exposures or it's only provides protection for 50% of people?
So, typically in drug trials there are efficacy measures and effectiveness measures. Drug trials measure efficacy: under controlled conditions with monitored outcomes, drug handling, prior conditions, etc. Effectiveness is a measure of 'real world' applications. For something like a vaccine that is intended for widespread distribution (vs. say, a diabetic drug or something) efficacy (typically) has a higher threshold bc the drug will be administered to people with backgrounds/medical histories, etc, that weren't included in the trials. Something with 50% efficacy would mean that the vaccine prevented half the experimental subjects from contracting the disease they are testing for. So with apparently two (+?) strains of corona going around, that complicates things. The other symptoms/complications, pre-existing conditions, etc. associated with covid infection also aren't included in the strict efficacy measure of a drug (unless specifically recruited during the trial- which could be an infinite combination, so no). And none of this includes an important aspect: side effects. Drugs are approved based on a balance of efficacy (and effectiveness for observational, non-clinical studies like some flu vaccines) and safety. No one wants a covid drug that makes their dick fall off, even if it's 100% effective.
It would be malpractice to rush out a vaccine that wasn't safe. It would be worse if they rushed one out and people felt invincible afterwards - you say you'd wear your mask and distance, but we already can't get ppl to do that without a vaccine. Shits only gonna get worse with a pseudo vaccine with minimal efficacy. To answer your actual question, it's debatable but highly unlikely that a vaccine with 50% efficacy would offer any help if youre on the wrong side of the dividing line. And 50% "effective" means that only half the people given the vaccine were protected from the specific disease they were testing and vaccinating for.
My post doc was working on clinical trials for Alzheimer's disease. It was a year and a half and I didn't see a single one to completion. If you believe an October timeline Ive got a bridge to sell you. I'm not up to date on all the different manufacturers and their statuses. But I'm not buying pre-sale Bonnaroo tickets either.
Question: say I get a first round vaccine that barely passes the sniff test of 50% effective. Given that I’m young and healthy, I’m willing to take that risk of me still catching the virus (would still wear my mask and distance when possible if it’s only 50% effective) but if I do, does that mean I’ll still have some sort of immunity and it won’t hit me as hard as it otherwise could?
Related question: When people say a vaccine is 50% effective, does that mean it only protects against 50% of exposures or it's only provides protection for 50% of people?
A vaccine that is 50% effective means it would reduce the average person’s risk of coronavirus infection by 50%. What most people don't realize is that the flu vaccine that you get every year is only 40-60% effective. A few years ago they found out it was about 35% effective. (they guessed badly that year) So yeah, it sucks, but they are taking the "it's better than nothing" approach. And it will keep you from getting as sick.
There will not be any data as to the percent effectiveness of the vaccine for awhile. Right now it's just safety and efficacy. The efficacy is if it builds up antibodies. It does not seem to do so in any appreciable amount until the second shot. Then it's how much and for how long.
But even fast tracking this, the hard fact of the matter is, the majority of the festival going crowd will not be able to get this vaccine right away. Distribution will be limited to health care workers first. As it should be. Then senior citizens and other populations hit the hardest, as well as those with pre-existing conditions. I can't see a scenario where everyone has it and can attend festivals until the end of next year.
But on a more positive note, the mother church of music is opening back up this Friday. The Ryman is hosting a live show with 125 people in attendance. Masks required.
I don’t even care about festivals coming back soon (beyond the fact that my job depends on it).I just want people to stop dying. My thought was that IF I can get one early on, I could potentially have less of a chance of getting/spreading it. Also, I’m the strictest person with COVID stuff I know so I don’t see the mask going anywhere till things get much better.
Are they any known risks to current vaccines that are rushed?
Or is it literally a healthcare pandora's box that could take 5, 10, 20+ years to truly manifest?
Well, I’m not dead yet. But it’s a crap shoot really. They aren’t bypassing any steps to make the vaccine, just speeding them up. Phase three is supposed to last two years. But if Trump has his way, they will ask the FDA for an emergency use authorization and put it out before phase three trials are done.
The two front runners in this thing are Moderna and Pfizer. I think Moderna is aware that Pfizer may win the race because they didn’t go through the NIH. Moderna doesn’t care. They want a vaccine that is proven safe and effective. They will only be a few months behind at best. And storage is a BIG issue. These two have to be kept frozen. As an immunizer I can tell you that is a pain in the butt. But several others have to be kept at -80 degrees. I don’t have anything in my pharmacy that will keep it at that. So good luck with that vaccine.
I don’t even care about festivals coming back soon (beyond the fact that my job depends on it).I just want people to stop dying. My thought was that IF I can get one early on, I could potentially have less of a chance of getting/spreading it. Also, I’m the strictest person with COVID stuff I know so I don’t see the mask going anywhere till things get much better.
New poll shows 2/3 of Americans won’t get vaccine when it first comes out, so I don’t think you will have that many people in line in front of you.
I don’t even care about festivals coming back soon (beyond the fact that my job depends on it).I just want people to stop dying. My thought was that IF I can get one early on, I could potentially have less of a chance of getting/spreading it. Also, I’m the strictest person with COVID stuff I know so I don’t see the mask going anywhere till things get much better.
New poll shows 2/3 of Americans won’t get vaccine when it first comes out, so I don’t think you will have that many people in line in front of you.
I more meant that I’m young and healthy so from what I gather it should get around to me last.
I don’t even care about festivals coming back soon (beyond the fact that my job depends on it).I just want people to stop dying. My thought was that IF I can get one early on, I could potentially have less of a chance of getting/spreading it. Also, I’m the strictest person with COVID stuff I know so I don’t see the mask going anywhere till things get much better.
New poll shows 2/3 of Americans won’t get vaccine when it first comes out, so I don’t think you will have that many people in line in front of you.
I'm going to follow my parents lead on this one, because my mom works at the hospital, and has told me that multiple employees have signed up for the first round already. She doesn't want the first round because of her suspicions (this is a big part of the black community, and I think the world's history on testing medicine on the poor and poc have a huge affect), but is also openly waiting for a safe vaccine. She seems to have more faith in Moderna than Pfizer, and that checks out with the timeline you were discussing.
I know that I have to make a serious consideration, that I'm "young" and will not be the aim of the vaccines first round, but sides of my industry depends on a vaccine happening Q1/Q2 of 2021 or MASS precautions. I don't have faith in people enough right now in my field to stay masked up all the way to Summer 2021, and that is an anxiety causing situation.
As a healthcare worker, will it be mandatory for work? When it came to the flu, we were forced to wear a mask when anyone rejected the seasonal vaccine.
As a healthcare worker, will it be mandatory for work? When it came to the flu, we were forced to wear a mask when anyone rejected the seasonal vaccine.
It will be every medical facilities call. But I’m going to guess it will be mandatory. I’ve given a bunch of flu shots already and some are healthcare workers that require proof of vaccination.
As a healthcare worker, will it be mandatory for work? When it came to the flu, we were forced to wear a mask when anyone rejected the seasonal vaccine.
when I worked in a hospital vaccines were always mandatory
Several drug makers developing Covid-19 vaccines plan to issue a public pledge not to seek government approval until the shots have proven to be safe and effective, an unusual joint move among rivals that comes as they work to address concerns over a rush to mass vaccination.
So one of my friends originally had a wedding schedule for early May this year, then they postponed it until December 5th thinking they'd be able to have it then. Just got a text saying that they'd like to have the wedding on October 24th now. For context, I've been extremely close friends with this guy since we were in like 2nd grade, and I'm one of the groomsmen. The wedding is Indiana (where covid doesn't really exist according to the people who live there), it's indoors, and he said there would be 100 people there. He said they're going to do the wedding, and have a reception after. The reception will only be 2-3 hours long apparently, will not have a DJ/dancing, and there will be the usual speeches and first dance/father daughter/mother son dance, and maybe a couple of other usual wedding things. He asked if me and my girlfriend will be attending.
First off, I'm really fucking pissed I'm in this situation in the first place. Who in their right fucking mind thinks it's a good idea to have an indoor wedding right now with that many people? I'm trying to empathize with their situation a little bit. I'm not getting married quite yet, and I know it must suck that they had to cancel their big day. Plus there are some outside factors at play too. They've wanted to move in together for quite some time, but the bride's parents are uber religious and basically had enough say to forbid since they were helping her pay her way through medical school. They finally moved in together after she graduated on the condition they were married asap.
I told my girlfriend she doesn't have to go at all even if I do. I really don't want to go, but I'm worried it might strain my friendship with this person, and I don't have a large number of friends and we share a lot of the same friends so it would be really awkward. I'm not as close with the other groomsmen, but I know I'd be the only one of them not attending if I don't go. I'm contemplating just wearing a mask the whole time, not taking it off except for like necessary pictures, and then not drinking at all or hanging out afterwards and just driving home as soon as feasibly possible. But I'm really not comfortable going. I have no idea what to do.
So one of my friends originally had a wedding schedule for early May this year, then they postponed it until December 5th thinking they'd be able to have it then. Just got a text saying that they'd like to have the wedding on October 24th now. For context, I've been extremely close friends with this guy since we were in like 2nd grade, and I'm one of the groomsmen. The wedding is Indiana (where covid doesn't really exist according to the people who live there), it's indoors, and he said there would be 100 people there. He said they're going to do the wedding, and have a reception after. The reception will only be 2-3 hours long apparently, will not have a DJ/dancing, and there will be the usual speeches and first dance/father daughter/mother son dance, and maybe a couple of other usual wedding things. He asked if me and my girlfriend will be attending.
First off, I'm really fucking pissed I'm in this situation in the first place. Who in their right fucking mind thinks it's a good idea to have an indoor wedding right now with that many people? I'm trying to empathize with their situation a little bit. I'm not getting married quite yet, and I know it must suck that they had to cancel their big day. Plus there are some outside factors at play too. They've wanted to move in together for quite some time, but the bride's parents are uber religious and basically had enough say to forbid since they were helping her pay her way through medical school. They finally moved in together after she graduated on the condition they were married asap.
I told my girlfriend she doesn't have to go at all even if I do. I really don't want to go, but I'm worried it might strain my friendship with this person, and I don't have a large number of friends and we share a lot of the same friends so it would be really awkward. I'm not as close with the other groomsmen, but I know I'd be the only one of them not attending if I don't go. I'm contemplating just wearing a mask the whole time, not taking it off except for like necessary pictures, and then not drinking at all or hanging out afterwards and just driving home as soon as feasibly possible. But I'm really not comfortable going. I have no idea what to do.
Yea I'm best man for a wedding in the middle of November. Indoors as far as I know. 150 people. Nervous AF.
So one of my friends originally had a wedding schedule for early May this year, then they postponed it until December 5th thinking they'd be able to have it then. Just got a text saying that they'd like to have the wedding on October 24th now. For context, I've been extremely close friends with this guy since we were in like 2nd grade, and I'm one of the groomsmen. The wedding is Indiana (where covid doesn't really exist according to the people who live there), it's indoors, and he said there would be 100 people there. He said they're going to do the wedding, and have a reception after. The reception will only be 2-3 hours long apparently, will not have a DJ/dancing, and there will be the usual speeches and first dance/father daughter/mother son dance, and maybe a couple of other usual wedding things. He asked if me and my girlfriend will be attending.
First off, I'm really fucking pissed I'm in this situation in the first place. Who in their right fucking mind thinks it's a good idea to have an indoor wedding right now with that many people? I'm trying to empathize with their situation a little bit. I'm not getting married quite yet, and I know it must suck that they had to cancel their big day. Plus there are some outside factors at play too. They've wanted to move in together for quite some time, but the bride's parents are uber religious and basically had enough say to forbid since they were helping her pay her way through medical school. They finally moved in together after she graduated on the condition they were married asap.
I told my girlfriend she doesn't have to go at all even if I do. I really don't want to go, but I'm worried it might strain my friendship with this person, and I don't have a large number of friends and we share a lot of the same friends so it would be really awkward. I'm not as close with the other groomsmen, but I know I'd be the only one of them not attending if I don't go. I'm contemplating just wearing a mask the whole time, not taking it off except for like necessary pictures, and then not drinking at all or hanging out afterwards and just driving home as soon as feasibly possible. But I'm really not comfortable going. I have no idea what to do.
Yea I'm best man for a wedding in the middle of November. Indoors as far as I know. 150 people. Nervous AF.
Of course, I’m pretty risk averse, and I think weddings are kind of silly anyway. I had two because we couldn’t get a marriage license for the one for my family, but my grandmother did all of the planning for the family one and the legal one was an Elvis wedding attended by a whopping seven friends.
Several drug makers developing Covid-19 vaccines plan to issue a public pledge not to seek government approval until the shots have proven to be safe and effective, an unusual joint move among rivals that comes as they work to address concerns over a rush to mass vaccination.
Moderna, J&J, and Pfizer.
Winston had a well-child visit today and his lovely pediatrician and I were talking about Covid and the future vaccine etc and she said "It's a scary day when you can trust the pharmaceutical companies more than our government"
A large, Phase 3 study testing a Covid-19 vaccine being developed by AstraZeneca and the University of Oxford at dozens of sites across the U.S. has been put on hold due to a suspected serious adverse reaction in a participant in the United Kingdom.
Well Fuck. There goes the Oxford vaccine. I hope the participant is going to be Ok.
Post by Dale Cooper on Sept 10, 2020 9:38:01 GMT -5
I'm groomsman in a wedding in two weeks. Its outdoors, thankfully. But idk what to do about the reception. Grab a plate, eat outside and then rock the mask inside at all times...