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I think venues in Texas can get by it by offering an "incentive" to people that "volunteer" proof of vaccination.
Like getting a seat where you can see the stage vs a seat in a Bonnaroo porta potty on Monday morning, right where the unvax'd belong. I think this is how the cruises out of Texas are getting around it.
Post by LoveLuckLaughter on Aug 3, 2021 9:12:00 GMT -5
A vaccinated family member in Arkansas, who has probably been even more careful than we have, was sick all weekend and just tested positive for COVID. The entire family is vaccinated except his two young children, who are home this summer with his wife who is a teacher. He works with a handful of deniers and Arkansas is full of the unvaccinated. Hopefully the kiddos will be okay.
We're all a mess of paradoxes. Believing in things we know can't be true. We walk around carrying feelings too complicated and contradictory to express. But when it all becomes too big, and words aren't enough to help get it all out, there's always music.
1/17 Spafford 2/7 Greensky Bluegrass 3/17 Cool Cool Cool 3/28 Ekoostik Hookah 7/10 Jason Mraz 7/11 Chris Stapleton 7/12 Red Hot Chili Peppers 7/13 Buffalo Ska Fest
Metro in Chicago just announced that you have to be fully vaccinated for entry to any show. Recent negative test will not be accepted. I hope the rest of concert venues here follow their example.
Came across these Reddit threads through the Bob Lefsetz blog. Doesn't bode well for all forthcoming fall tours, and seems to corroborate what that earlier tweet was saying about Live Nation not giving a fuck.
And all Live Nation said about that was this. But they know whats up.
This is a big fucking deal. Cause uf you got Garth doing this its gonna raise some eyebrows.
Post by crazykittensmile on Aug 3, 2021 15:00:43 GMT -5
Soooooo, it's totes reasonable to at home test the ~dozen people for covid as they arrive at my kid's birthday party next weekend, right?
It's his 4th birthday and the first one he's old enough to give a shit about and he won't stop talking about it, otherwise I'd cancel. It's also the first time all 5 cousins have been together in 2 years. It's 100% family members, and I'm sure they'd all be fine with it. All adults are vaccinated, but apparently that's not enough with delta.
I'd provide the tests, obviously. Like a really weird party favor... lol.
Came across these Reddit threads through the Bob Lefsetz blog. Doesn't bode well for all forthcoming fall tours, and seems to corroborate what that earlier tweet was saying about Live Nation not giving a fuck.
And all Live Nation said about that was this. But they know whats up.
This is a big fucking deal. Cause uf you got Garth doing this its gonna raise some eyebrows.
A comment from that Reddit poster said that it was the main act telling the supporting act to keep their mouth shut, in order not to piss off LN. So it sounds like an indirect gag order.
The guy posted another update: https://www.reddit.com/r/livesound/comments/ox9tk0/touring_during_a_pandemic_my_breakthrough_covid/
Soooooo, it's totes reasonable to at home test the ~dozen people for covid as they arrive at my kid's birthday party next weekend, right?
It's his 4th birthday and the first one he's old enough to give a shit about and he won't stop talking about it, otherwise I'd cancel. It's also the first time all 5 cousins have been together in 2 years. It's 100% family members, and I'm sure they'd all be fine with it. All adults are vaccinated, but apparently that's not enough with delta.
I'd provide the tests, obviously. Like a really weird party favor... lol.
crazykittensmile Send me those at home tests baby. My work schedule has gotten too insane and would feel better if there was a way to test myself and put worry out of my mind.
Soooooo, it's totes reasonable to at home test the ~dozen people for covid as they arrive at my kid's birthday party next weekend, right?
It's his 4th birthday and the first one he's old enough to give a shit about and he won't stop talking about it, otherwise I'd cancel. It's also the first time all 5 cousins have been together in 2 years. It's 100% family members, and I'm sure they'd all be fine with it. All adults are vaccinated, but apparently that's not enough with delta.
I'd provide the tests, obviously. Like a really weird party favor... lol.
I wonder if anyone thats going to get married soon is going to include that with the wedding invitation. That would be a great way to weed out who you do and who you dont want at the ceremony.
Friend of mine’s preschool teacher was fully vaccinated and had a breakthrough infection. This is Texas so no masks in the classroom. Two kids in the class got it from the teacher and are now hospitalized.
Tbh within your specific class, it doesn’t really matter if you’re masked. The kids eat their meals in the room and if they’re young enough, they’re also napping with no masks. Five days, 7 hours each day, is just too much time to be paranoid about. Plus they’re lil kids! It’s going to fall down, they forget when they drink water, they pick their noses etc etc. My goal is always to just keep it contained within our class. I was in school with kids from October 2 last year and we luckily didn’t not have any issues all year. We had a few other teachers get it over the year but it was always from outside school (family get togethers, bars, etc).
Tbh within your specific class, it doesn’t really matter if you’re masked. The kids eat their meals in the room and if they’re young enough, they’re also napping with no masks. Five days, 7 hours each day, is just too much time to be paranoid about. Plus they’re lil kids! It’s going to fall down, they forget when they drink water, they pick their noses etc etc. My goal is always to just keep it contained within our class. I was in school with kids from October 2 last year and we luckily didn’t not have any issues all year. We had a few other teachers get it over the year but it was always from outside school (family get togethers, bars, etc).
From everything I’ve read, kid to kid transmission is extremely rare, especially the real littles. So the fact they’re not great about wearing masks aren’t all day is t a huge deal. The real concern is whether the teachers are wearing masks, so they can’t spread it to the kids.
I wonder why that is? Because kids are usually disgusting little cootie factories. Do you have any sources on that?
Maybe their little lungs just don’t spread it as much? ¯\_(ツ)_/¯
there has been some discussion/hypotheses that younger people have more immunity to coronaviruses as a whole and this translates to Covid 19. The hypothesis is that children, especially school age children, encounter a greater variety of coronaviruses on a more regular basis than adults. Therefore their immune systems are primed to fight them. This leads to reduced symptoms, severity, and transmission (as lower viral loads and reduced symptoms generally correspond to reduced transmission). In other words, kids are less susceptible to and likely to transmit the virus precisely because they are “disgusting little cootie factories.”
I apologize in advance if you already knew about this theory. And please note that much of this theory was based on data from Covid “original recipe,” rather than delta.
chase rice is the most hick name i think ive ever heard
His 2020 hit song was "Drinkin' Beer. Talkin' God. Amen"
Feels like he tried to get as close to a platonic ideal title of a contemporary country song title as possible, but nobody can take that title away from “John Cougar, John Deere, and John 3:16”.
Maybe their little lungs just don’t spread it as much? ¯\_(ツ)_/¯
there has been some discussion/hypotheses that younger people have more immunity to coronaviruses as a whole and this translates to Covid 19. The hypothesis is that children, especially school age children, encounter a greater variety of coronaviruses on a more regular basis than adults. Therefore their immune systems are primed to fight them. This leads to reduced symptoms, severity, and transmission (as lower viral loads and reduced symptoms generally correspond to reduced transmission). In other words, kids are less susceptible to and likely to transmit the virus precisely because they are “disgusting little cootie factories.”
I apologize in advance if you already knew about this theory. And please note that much of this theory was based on data from Covid “original recipe,” rather than delta.
this is kind of partially right. the milder symptoms/less transmissability is more likely due to the way that kids fight off diseases, and not exposure variety. (think about it - in 35 years i've encountered many, many more pathogens than my 4 year old, and my immune system has adapted accordingly).
Kids have what's called an innate immune system. Unlike the adaptive immune system in adults (e.g. specific antibodies for different pathogens), the innate immune system basically acts like a generalized safety net that attacks any sort of invader in a non-specific way. It's inherited from the parents (and physical barriers like mucous membranes, skin, etc. are considered a part of this). This recent journal article post from Nature found the T-cell (adaptive immune response) responses of children were dampened, and overall counts were lower (even when accouting for age) in infected children vs. adults. basically, there is a much lower adaptive response to the virus:
The differences between infected children and adults may be due to differences in prior immunity to seasonal human coronaviruses through infection50, resulting in qualitative differences in antigen-experienced CD4+ T cell responses in children. Children experience greater fold changes in influenza-specific T cell responses compared to adults during live attenuated influenza vaccination51, whereas we found lower SARS-CoV-2 T cell response magnitudes in children, however their fold changes and polyfunctional cytokines of the T cell responses was comparable between adults and children. Therefore there is equal recruitment of SARS-CoV-2 T cell responses in adults and children but likely different baseline levels of cross-reactive responses to recruit from, which is also indicated by increased Tfh recruitment in children for driving antibody responses, higher effector memory T cells in adults, and higher β-coronavirus OC43 specific IgG in adults. The smaller magnitude of SASR-CoV-2 memory T cell responses in children than adults, may imply a weaker long-term memory response in children potentially impacting outcomes at reinfection...
The quality of T cell responses, assessed by SARS-CoV-2 specific T cell polyfunctional cytokine production and exhaustion marker (PD-1) expression, was equivalent between children and adults, reflecting comparable division and terminal differentiation. The matched quality of response but the higher threshold for IFNγ production by T cells in children may drive a less inflammatory environment that promotes more mild COVID-19 outcomes in children. There was different recruitment of innate and adaptive cellular responses in adults and children during SARS-CoV-2 infection likely driven by a difference in inflammatory milieu despite comparable symptom severity (mild/asymptomatic in our study). Children had increased Tfh recruitment, comparable plasmablast responses, but reduced inflammatory monocytes, specific CD4+ and CD8+ T cell responses, in both magnitude and proportion of responders...
Previously, in MERS-CoV infection, the magnitude of the CD4+ T cell response is proportional to virus replication and duration of illness. This is consistent with the mild outcomes of COVID-19 in children and reduced T cell responses reported here in our study of mild and asymptomatic SARS-CoV-2 infection. We cannot attribute the differences in T cell response magnitude with the severity of illness in children to adults, unlike other reports, as the majority of both infections we studied are mild or asymptomatic. Therefore children have reduced SARS-CoV-2 T cell responses due to lower baseline immune activation, and further research is still needed to discern the protective role of T cells in COVID-19.
Here's another paper from cell that links robust naive T cell mechanisms reduce severity of symptoms (it was all adults, but as you age your adaptive immunity decreases; thus older people have less robust t-cell immune responses, hence worse outcomes generally).
T-cells are the lymphocytes that are responsible for cell immunity (killing off infected cells). B-cell are responsible for stuff in the fluids of your body (they are activated by stuff in your blood).
this article from science looks at B-cell responses to Corona virus from children. it's pretty short and is a retrospective sort of analysis looking at age-related B-cell responses to common pathogens and novel exposure to Ebola and covid.
We find that in comparison to adults, children have higher frequencies of convergent B cell clones in their blood for pathogens they have encountered. Notably, prepandemic children also had class-switched convergent clones to SARS-CoV-2 and its viral variants, but not EBOV, at higher frequencies than adults. We hypothesize that previous HCoV exposures may stimulate cross-reactive memory, and that such clonal responses may have their highest frequencies in childhood. The caveats of our analysis are that convergent clones may not fully represent the properties of all pathogen-specific clones in an individual and that binding affinities for cross-reactivity that would be relevant in vivo are not known.
Taken together, basically it appears that the innate immune system of kids may prevent a lot of the inital viral load just through sheer force of non-specific immune response. Kids t-cell responses were proportionately lower because they do not have the same adaptive immune response as adults but their B-cell responses are faster because they use this clonal mechanism to adapt faster.
Granted, these are just a couple papers I read most recently, and I am not an immunologist/infectious disease expert. I just have kids and work in a kids cancer hospital, so I've been reading (and presented with) a lot of material lately. Another thing that I've seen brought up is also just in the basic physics of viral transmission: children have lower genetic expression for ACE2 receptors (where the virus binds) in nasal epithelium. Basically fewer ports where the virus can dock. (JAMA)
caveat: these studies aren't specific for the delta variant.
there has been some discussion/hypotheses that younger people have more immunity to coronaviruses as a whole and this translates to Covid 19. The hypothesis is that children, especially school age children, encounter a greater variety of coronaviruses on a more regular basis than adults. Therefore their immune systems are primed to fight them. This leads to reduced symptoms, severity, and transmission (as lower viral loads and reduced symptoms generally correspond to reduced transmission). In other words, kids are less susceptible to and likely to transmit the virus precisely because they are “disgusting little cootie factories.”
I apologize in advance if you already knew about this theory. And please note that much of this theory was based on data from Covid “original recipe,” rather than delta.
this is kind of partially right. the milder symptoms/less transmissability is more likely due to the way that kids fight off diseases, and not exposure variety. (think about it - in 35 years i've encountered many, many more pathogens than my 4 year old, and my immune system has adapted accordingly).
Kids have what's called an innate immune system. Unlike the adaptive immune system in adults (e.g. specific antibodies for different pathogens), the innate immune system basically acts like a generalized safety net that attacks any sort of invader in a non-specific way. It's inherited from the parents (and physical barriers like mucous membranes, skin, etc. are considered a part of this). This recent journal article post from Nature found the T-cell (adaptive immune response) responses of children were dampened, and overall counts were lower (even when accouting for age) in infected children vs. adults. basically, there is a much lower adaptive response to the virus:
The differences between infected children and adults may be due to differences in prior immunity to seasonal human coronaviruses through infection50, resulting in qualitative differences in antigen-experienced CD4+ T cell responses in children. Children experience greater fold changes in influenza-specific T cell responses compared to adults during live attenuated influenza vaccination51, whereas we found lower SARS-CoV-2 T cell response magnitudes in children, however their fold changes and polyfunctional cytokines of the T cell responses was comparable between adults and children. Therefore there is equal recruitment of SARS-CoV-2 T cell responses in adults and children but likely different baseline levels of cross-reactive responses to recruit from, which is also indicated by increased Tfh recruitment in children for driving antibody responses, higher effector memory T cells in adults, and higher β-coronavirus OC43 specific IgG in adults. The smaller magnitude of SASR-CoV-2 memory T cell responses in children than adults, may imply a weaker long-term memory response in children potentially impacting outcomes at reinfection...
The quality of T cell responses, assessed by SARS-CoV-2 specific T cell polyfunctional cytokine production and exhaustion marker (PD-1) expression, was equivalent between children and adults, reflecting comparable division and terminal differentiation. The matched quality of response but the higher threshold for IFNγ production by T cells in children may drive a less inflammatory environment that promotes more mild COVID-19 outcomes in children. There was different recruitment of innate and adaptive cellular responses in adults and children during SARS-CoV-2 infection likely driven by a difference in inflammatory milieu despite comparable symptom severity (mild/asymptomatic in our study). Children had increased Tfh recruitment, comparable plasmablast responses, but reduced inflammatory monocytes, specific CD4+ and CD8+ T cell responses, in both magnitude and proportion of responders...
Previously, in MERS-CoV infection, the magnitude of the CD4+ T cell response is proportional to virus replication and duration of illness. This is consistent with the mild outcomes of COVID-19 in children and reduced T cell responses reported here in our study of mild and asymptomatic SARS-CoV-2 infection. We cannot attribute the differences in T cell response magnitude with the severity of illness in children to adults, unlike other reports, as the majority of both infections we studied are mild or asymptomatic. Therefore children have reduced SARS-CoV-2 T cell responses due to lower baseline immune activation, and further research is still needed to discern the protective role of T cells in COVID-19.
Here's another paper from cell that links robust naive T cell mechanisms reduce severity of symptoms (it was all adults, but as you age your adaptive immunity decreases; thus older people have less robust t-cell immune responses, hence worse outcomes generally).
T-cells are the lymphocytes that are responsible for cell immunity (killing off infected cells). B-cell are responsible for stuff in the fluids of your body (they are activated by stuff in your blood).
this article from science looks at B-cell responses to Corona virus from children. it's pretty short and is a retrospective sort of analysis looking at age-related B-cell responses to common pathogens and novel exposure to Ebola and covid.
We find that in comparison to adults, children have higher frequencies of convergent B cell clones in their blood for pathogens they have encountered. Notably, prepandemic children also had class-switched convergent clones to SARS-CoV-2 and its viral variants, but not EBOV, at higher frequencies than adults. We hypothesize that previous HCoV exposures may stimulate cross-reactive memory, and that such clonal responses may have their highest frequencies in childhood. The caveats of our analysis are that convergent clones may not fully represent the properties of all pathogen-specific clones in an individual and that binding affinities for cross-reactivity that would be relevant in vivo are not known.
Taken together, basically it appears that the innate immune system of kids may prevent a lot of the inital viral load just through sheer force of non-specific immune response. Kids t-cell responses were proportionately lower because they do not have the same adaptive immune response as adults but their B-cell responses are faster because they use this clonal mechanism to adapt faster.
Granted, these are just a couple papers I read most recently, and I am not an immunologist/infectious disease expert. I just have kids and work in a kids cancer hospital, so I've been reading (and presented with) a lot of material lately. Another thing that I've seen brought up is also just in the basic physics of viral transmission: children have lower genetic expression for ACE2 receptors (where the virus binds) in nasal epithelium. Basically fewer ports where the virus can dock. (JAMA)
caveat: these studies aren't specific for the delta variant.